题 目：Protein Synthesis with Non-canonical Amino Acids In Vitro and In Vivo
报告人：Sidney M. Hecht 教授
时 间：2019年5月12日（上午10:00~ ）
Sidney Hecht obtained his Ph.D. in Chemistry at the University of Illinois. Following studies as an NIH Postdoctoral Fellow in Molecular Biology at the University of Wisconsin, he was a member of the MIT Chemistry faculty from 1971-79. He was the John W. Mallet Professor of Chemistry and Professor of Biology at UVa from 1978-2008. From 1981-87 he held concurrent appointments at Smith Kline & French Laboratories, first as Vice President Preclinical R&D, then as Vice President Chemical R&D. Since 2008 he has been Director of the Center for BioEnergetics in the Biodesign Institute, and Professor of Chemistry at Arizona State University. He has been an Alfred P. Sloan Fellow, and a John Simon Guggenheim Fellow. Hecht received the 1996 Cope Scholar Award of the ACS and was selected as Virginia’s Outstanding Scientist for 1996. He received the 1998 Research Achievement Award of the American Society of Pharmacognosy and is a Fellow of the American Association for the Advancement of Science, and of the American Society of Pharmacognosy. He received the ASU Faculty Achievement Award in Defining Edge Research: Innovation (2011) and was recently elected a Senior Member, National Academy of Inventors (2019). He has been an Associate Editor of the Journal of the American Chemical Society since 1992.
His research interests include the synthesis and mechanism of action of bleomycin group antitumor agents. At ASU, he is studying the chemistry of the mitochondrial electron transport chain with the goal of devising therapeutic strategies to treat mitochondrial diseases. Other research interests include the elaboration and study of proteins containing synthetic amino acids.